Figure 3. Cocaine pretreatment enhanced ventral hippocampal NMDA-stimulated motor activity and extracellular dopamine in the nucleus accumbens.
Effects of ventral hippocampal NMDA infusion on (A) motoric activity and (B) extracellular DA in the nucleus accumbens of saline (N=9) and cocaine (N=10) pre-treated rats, expressed as percentage of baseline. Arrow indicates time of NMDA infusion. Data represent mean ± SEM. # significantly different from pre-infusion levels in both saline- and cocaine-pre-treated rats. * Significant difference between saline- and cocaine-pretreated groups (P < 0.05).