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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Neurochem. 2014 Jun 23;130(4):583–590. doi: 10.1111/jnc.12764

Figure 4. Effect of repeated cocaine on NMDA receptor subunit expression in the ventral hippocampus.

Figure 4

(A) Representative protein bands on immunoblots for NR1 (120 kD), NR2A (180 kD), and NR2B (190 kD) in the ventral hippocampus (examples are from single animals in each treatment group). (B) NMDA subunit protein levels in ventral hippocampal tissue of saline- and cocaine-administered rats. (C) Calculated NR2A:NR2B ratios of rats injected with saline or cocaine for seven days. Repeated cocaine resulted in a reduced NR2A:NR2B ratio in the ventral hippocampus compared with repeated saline (*significant difference between saline and cocaine groups, P < 0.05). Means + SEM are shown. (N=9–10/group)