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. Author manuscript; available in PMC: 2015 Aug 5.
Published in final edited form as: Cell Metab. 2014 Jun 26;20(2):333–345. doi: 10.1016/j.cmet.2014.05.021

Figure 5.

Figure 5

Tb, TEE, and RER response of melanocortin receptor mutant mice to MTII. (A) Mc1r e/e (21.6 ±0.3 g) and wild type (23.3 ±0.8 g) male mice, n=6/group. (B) Mc3r−/− (27.3 ±0.6 g) and wild type (27.0 ±0.5 g) male mice, n=12/group. (C) Mc4r−/− (54.1 ±1.0 g) and wild type (29.3 ±0.6 g) male and female mice, n=4–6/group. (D) Mc5r−/− (23.3 ±0.6 g) and wild type (22.3 ±0.6 g) male mice, n=6/group. (E) Mc3r−/−;Mc4r−/− (42.7 ±1.6 g) and wild type (25.6 ±0.8 g) male and female mice, n=6/ group. (F) Avy/+ (30.3 ±1.5 g) and wild type (22.5 ±0.6 g) female mice, n=5/group. (G) Mc3r−/−; Avy/+ (37.6 ±2.0 g, n=5) and wild type (28.5 ±0.5 g, n=9) male mice, crossover design. Every tenth symbol and SEM are shown for visual clarity.