Table 2.
Incidence and percentage of malignant transformation [2, 4, 6, 7, 9, 11–13, 16, 18–24, 26, 27, 29–31, 33–35, 37–40]
| References | Total no. of papillomas | No. of carcinomas | Synchronous | Metachronous | % Carcinoma |
|---|---|---|---|---|---|
| Norris [11] | 28 | 1 | 1 | 0 | 4 |
| Norris [12] | 29 | 2 | 1 | 1 | 7 |
| Skolnick [33] | 33 | 5 | 1 | 4 | 15 |
| Hyams [23] | 149 | 19 | n/r | n/r | 13 |
| Snyder [13] | 39 | 8 | 7 | 1 | 21 |
| Lasser [24] | 17 | 4 | 2 | 2 | 24 |
| Ridolfi [30] | 30 | 1 | 0 | 1 | 3 |
| Abildgaard-Jensen [20] | 21 | 3 | 2 | 1 | 14 |
| Kristensen [38] | 83 | 7 | 4 | 3 | 8 |
| Woodson [35] | 90 | 4 | 1 | 3 | 4 |
| Christensen [21] | 39 | 7 | 6 | 1 | 18 |
| Segal [31] | 30 | 3 | 0 | 3 | 10 |
| Weissler [21] | 223 | 11 | 8 | 3 | 5 |
| Klemi [7] | 19 | 3 | 2 | 1 | 16 |
| Myers [26] | 33 | 7 | 5 | 2 | 21 |
| Phillips [29] | 112 | 8 | 8 | 0 | 7 |
| Furuta [22] | 26 | 7 | 5 | 2 | 27 |
| Outzen [27] | 67 | 1 | 0 | 1 | 2 |
| Dolgin [4] | 42 | 5 | 4 | 1 | 12 |
| Bielamowicz [19] | 61 | 10 | 5 | 5 | 16 |
| Kapadia [6] | 800 | 56 | n/r | n/r | 7 |
| Vrabec [16] | 101 | 8 | 7 | 1 | 8 |
| Beck [18] | 39 | 10 | 3 | 7 | 26 |
| Lawson [39] | 112 | 6 | 4 | 2 | 5 |
| Lesperance [9] | 51 | 14 | 6 | 8 | 27 |
| Buchwald [2] | 57 | 5 | 3 | 2 | 9 |
| Nachtigal [40] | 72 | 8 | n/r | n/r | 11 |
| Kaufman [37] | 34 | 3 | 2 | 1 | 9 |
| Current series | 740 | 14 | 9 | 5 | 1.9 |
| Total | 3,177 | 240 | 100 | 63 | 7.6 |