Table 1.
Description of participants by level of kidney function
| Variables | Control group | Group A | Group B | Group C | F or χ 2 | P for trend |
|---|---|---|---|---|---|---|
| N | 50 | 141 | 72 | 73 | – | – |
| Female | 26 (52.0 %) | 77 (%) | 32 (54.6 %) | 32 (44.4 %) | 3.265 | 0.353 |
| Age (years) | 49.48 ± 10.54 | 49.87 ± 14.53 | 51.10 ± 14.87 | 48.33 ± 17.59 | 0.430 | 0.732 |
| BMI (kg/m2) | 23.49 ± 3.91 | 23.61 ± 3.97 | 24.36 ± 3.61 | 23.28 ± 2.75 | 1.184 | 0.361 |
| eGFR (ml/min 1.73/m2) | 123.16 ± 12.31 | 121.60 ± 24.82 | 75.55 ± 8.46▲ | 43.01 ± 8.09◆ | 389.372 | <0.001 |
| Hb (g/l) | 136.56 ± 10.95 | 130.98 ± 22.92 | 130.24 ± 18.21 | 118.65 ± 21.64★,▲,◆ | 9.100 | <0.001 |
| Ca (mmol/l) | – | 2.15 ± 0.19 | 2.16 ± 0.18 | 2.13 ± 0.16 | 0.395 | 0.647 |
| P (mmol/l) | – | 1.28 ± 0.43 | 1.19 ± 0.21 | 1.18 ± 0.21 | 2.238 | 0.109 |
| Log iPTH (µg/l) | 3.25 ± 0.58 | 3.61 ± 0.41★ | 3.82 ± 0.33△ | 4.10 ± 0.77◆ | 29.644 | <0.001 |
| CRP (mg/l) | – | 2.68 ± 6.40 | 5.23 ± 9.87 | 8.12 ± 9.82▲ | 10.454 | <0.001 |
| ACR (mg/mmol) | – | 117.32 ± 58.28 | 98.30 ± 48.20 | 641.57 ± 335.52 | 1.591 | 0.205 |
| TG (mmol/l) | 1.95 ± 0.89 | 1.86 ± 0.87 | 1.73 ± 0.65 | 1.77 ± 0.83 | 0.374 | 0.772 |
| Log-Tch | 1.55 ± 0.47 | 1.59 ± 0.35 | 1.61 ± 0.25 | 1.64 ± 0.45 | 0.989 | 0.414 |
| HDL (mmol/l) | 1.25 ± 0.33 | 1.17 ± 0.49 | 1.06 ± 0.35 | 1.04 ± 0.34★ | 3.448 | 0.017 |
| Log LDL (mmol/l) | 1.00 ± 0.49 | 0.97 ± 0.41 | 1.11 ± 0.34 | 1.01 ± 0.42 | 1.774 | 0.152 |
| SBP (mmHg) | 117.04 ± 7.28 | 126.35 ± 11.45★ | 131.69 ± 18.69 | 141.55 ± 19.34◆ | 30.610 | <0.001 |
| DBP (mmHg) | 75.32 ± 6.21 | 77.59 ± 8.80 | 81.19 ± 9.93★ | 84.11 ± 12.09★,▲ | 11.496 | <0.001 |
| Prevalence of hypertension | 0 (0.0 %) | 14 (9.9 %) | 46 (31.9 %) | 18 (67.1 %) | 103.02 | <0.001 |
Bold values indicate statistically significant
Compared with the control group, ★ P < 0.01
Compared with Group A, △ P < 0.05; ▲ P < 0.01
Compared with Group B, ◆ P < 0.01