Table 2.

Results from psychophysiological interaction analyses with left and right VH as seed regions

Seed region	Target region	Effect	Peak coordinates a			t -value
			x	y	z
L VH	Left amygdala	GS 3 > vCS−	−23	−3	−12	4.74
	Right anterior insula	GS 3 > vCS−	43	10	−7	4.96
	vmPFC	vCS−> GS 3	1	23	−12	4.45
	Right amygdala	All rings > vCS−	24	−1	−13	7.13
	Right anterior insula	All rings > vCS−	36	7	−1	6.05
R VH	Right amygdala	GS 3 > vCS−	22	−2	−9	4.66
	Right anterior insula	GS 3 > vCS−	45	6	−7	4.11
	Precuneus	vCS−> GS 3	6	−59	15	5.22
	vmPFC	vCS−> GS 3	0	23	−13	4.12
	Right anterior insula	All rings > vCS−	44	11	−8	5.15
	vmPFC	vCS−> all rings	−5	45	−7	3.91

^a LPI.

L = left; R = right; VH = ventral hippocampus; vmPFC = ventromedial prefrontal cortex; GS ₃ = generalization stimulus most similar to conditioned danger cue; vCS− = ‘v-shaped’ conditioned safety cue; all rings = average response across all ringed stimuli (i.e. oCS−, GS ₁ , GS ₂ , GS ₃ and CS+). All effects were significant at P ≤ 0.001, uncorrected.