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. Author manuscript; available in PMC: 2014 Aug 9.
Published in final edited form as: J Invest Dermatol. 2008 May 29;128(10):2508–2517. doi: 10.1038/jid.2008.131

Figure 4. Incomplete repair of thymine dimers in VDR−/− epidermis compared to wildtype.

Figure 4

Newborn mice were exposed to 120mJ/cm2 of UV and skin was collected at the indicated time points. Epidermal genomic DNA was isolated and thymine dimers were measured by southwestern slot blot. Thymine dimers were normalized to total genomic DNA with a radiolabeled mouse genomic DNA probe. Thymine dimers were measured in the epidermis of 2–3 individual mice for each time point, except for the unirradiated control. The data shown represents the mean from three independent measurements of thymine dimers relative to total genomic DNA from the epidermal samples. Error bars = SEM. *P<0.04