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. Author manuscript; available in PMC: 2014 Aug 9.
Published in final edited form as: J Neurosci Res. 2008 Nov 1;86(14):3096–3105. doi: 10.1002/jnr.21765

Figure 2.

Figure 2

Concentration-response of BzATP on DNA synthesis induced by FGF2. Quiescent cultures of rat cortical astrocytes were treated with FGF2 (25 ng/ml) or in combination with concentrations of BzATP ranging from 1 to 100 uM, and DNA synthesis was measured as described in Materials and Methods. Thymidine incorporation in FGF2-treated cultures was increased 606 ± 109 % (Mean ± SEM, n = 3) compared to control cultures. Data from cultures treated with FGF2 and BzATP are expressed as %FGF2. DNA synthesis induced by FGF2 was significantly decreased by 30 uM and 100 uM BzATP (* p<0.01).