Table 4.
Estimated probabilities (%) of morbidity and mortality from untreated SNPTB and side effects in treated SNPTB (median and inter quartile range)
| India (n = 77) | Pakistan (n = 84) | Bangladesh (n = 81) | All countries (n = 242) | ||
|---|---|---|---|---|---|
| 1 |
Mortality from untreated SNPTB* |
70 (65-75) |
60 (30-82.5) |
60 (40-70) |
65 (50-75) |
| 2 |
Morbidity from untreated SNPTB¶ |
5 (5-10) |
20 (10-30) |
29.5 (20-30) |
20 (8-30) |
| 3 |
Probability of side effects occurring if SNPTB is treated¶ |
6 (3-9) |
10 (5-20) |
15 (10-29) |
10 (5-20) |
| 4 |
Conditional probability of death due to side effects if they occur when SNPTB is treated¶ |
5 (3-5) |
10 (4.5-20) |
12.5 (5-25) |
8 (5-20) |
| 5 |
Conditional probability of morbidity as a result of side effects when SNPTB is treated¶ |
10 (7-15) |
25 (10-50) |
15 (10-30) |
15 (10-30) |
| 6 |
Absolute probability of mortality arising from side effects of anti-TB treatment¶× |
0.25 (0.11-0.45) |
1.5 (0.71-10) |
1(0.22-4.0) |
0.70 (0.23-3.1) |
| 7 | Absolute probability of morbidity arising from side effect of anti-TB treatment¶π | 0.6 (0.3-1) | 3.0 (1-7.4) | 3 (0.57-8) | 1.5 (0.6-4.6) |
¶p < 0.001.
× Calculated as row 3 × row 4.
π calculated as row 3 × row 5.
*p < 0.01.