Table 1.
Agent | Equivalent dose (mg) | AI potency | Classification |
---|---|---|---|
Hydrocortisone | 20 | 1 | Short to medium acting GC |
Cortisone | 25 | 0.8 | Short to medium acting GC |
Prednisone | 5 | 4 | Short to medium acting GC |
Prednisolone | 5 | 4 | Short to medium acting GC |
Methylprednisolone | 4 | 5 | Short to medium acting GC |
Triamcinolone | 4 | 5 | Intermediate acting GC |
Betamethasone | 0.6 | 25-40 | Long acting GC |
Dexamethasone | 0.75 | 30 | Long acting GC |
Fludrocortisone | 2 | 10 | Mineralocorticoid |
AI: Anti-Inflammatory, GC: Glucocorticoid |
COPD Exacerbation Management Quick Facts:
- COPD guidelines centered around 2008 GOLD recommendations
-
Prednisone 30-40 mg PO Daily x 7-14 days is recommended exacerbation treatment
- No additional benefit seen beyond two weeks of therapy
- PO is preferred route of steroid administration over IV