Table 5.
Molecular markers of anti-folate resistance in Plasmodium falciparum isolates collected through the National Antimalarial Drug Resistance Monitoring System, northeast India, 2012-2013
| |
dhfr
(N = 155) |
dhps
(N = 155) |
||
|---|---|---|---|---|
| Mutations | n | Haplotype | n | Haplotype |
| Quadruple |
5 |
I51/R59/N108/L164 |
1 |
A436/G437/E540/A581/T613 |
| |
|
|
35 |
A436/G437/E540/G581/A613 |
| Triple |
69 |
I51/R59/N108/I164 |
75 |
A436/G437/E540/A581/A613 |
| |
7 |
N51/R59/N108/L164 |
6 |
A436/G437/K540/G581/A613 |
| |
|
|
5 |
S436/G437/E540/G581/A613 |
| Double |
71 |
N51/R59/N108/I164 |
11 |
S436/G437/E540/A581/A613 |
| |
|
|
1 |
A436/A437/E540/A581/A613 |
| |
|
|
2 |
S436/A437/E540/G581/A613 |
| |
|
|
9 |
S436/G437/K540/G581/A613 |
| Single |
3 |
N51/C59/N108/I164 |
1 |
S436/A437/E540/A581/A613 |
| |
|
|
2 |
S436/G437/K540/A581/A613 |
| |
|
|
1 |
S436/A437/K540/G581/A613 |
| Wild | 6 | S436/A437/K540/A581/A613 | ||
*Mutations in bold.