Table 1.
Study cohorts comprising the SIGMA T2D Project dataset with sample location, study design, numbers of cases and controls (including numbers before quality control (QC) checks), % male participants, age ± standard deviation (SD), age-of-onset in cases ± SD, body mass index ± SD, and fasting plasma glucose in controls ± SD.
| Study | Sample Location | Study Design | N (Before QC) | % Male | Age (years) | Age-of- onset (years) | Body mass index (kg/m2) | Fasting plasma glucose (mmol/l) | |
|---|---|---|---|---|---|---|---|---|---|
| UNAM/INCMNSZ Diabetes Study (UIDS) | Mexico City, Mexico | Prospective Cohort | Controls | 1,138 (1,195) | 41.1% | 55.3 ± 9.4 | – | 28.1 ± 4.0 | 4.8 ± 0.5 |
| T2D Cases | 815 (872) | 40.9% | 56.2 ± 12.3 | 44.2 ± 11.3 | 28.4 ± 4.5 | – | |||
| Diabetes in Mexico Study (DMS) | Mexico City, Mexico | Prospective Cohort | Controls | 472 (505) | 25.8% | 52.5 ± 7.7 | – | 28.0 ± 4.4 | 5.0 ± 0.4 |
| T2D Cases | 690 (762) | 33.0% | 55.8 ± 11.1 | 47.8 ± 10.6 | 29.0 ± 5.4 | – | |||
| Mexico City Diabetes Study (MCDS) | Mexico City, Mexico | Prospective Cohort | Controls | 613 (790) | 39.3% | 62.5 ± 7.7 | – | 29.4 ± 4.8 | 5.0 ± 0.5 |
| T2D Cases | 287 (358) | 41.1% | 64.2 ± 7.5 | 55.1 ± 9.7 | 29.9 ± 5.4 | – | |||
| Multiethnic Cohort (MEC) | Los Angeles, California, USA | Case- Control | Controls | 2,143 (2,464) | 48.3% | 59.3 ± 7.0 | – | 26.6 ± 3.9 | N/A |
| T2D Cases | 2,056 (2,279) | 47.9% | 59.2 ± 6.9 | N/A | 30.0 ± 5.4 | – |