Fig. 3.

Interaction network of E. coli divisome proteins. Blue lines indicate interactions that were observed both in vitro and in cells. Red lines represents interactions identified only in bacterial two-hybrid screening (in two-hybrid assays (Karimova et al. 2005), protein interactions bring together the binding and activating domains of a transcription factor that turns on a reporter gene). For an extensive review of the raw interaction data that were used to build this interaction graph, see Egan and Vollmer (2013). (Color figure online)