| (i) Previous preeclampsia (PE) |
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| (ii) Previous early onset PE and preterm delivery at <34 weeks' gestation |
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| (iii) PE in more than one prior pregnancy |
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| (iv) Chronic kidney disease |
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| (v) Autoimmune disease such as systemic lupus erythematosis or antiphospholipid syndrome |
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| (vi) Heritable thrombophilias |
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| (vii) Type 1 or type 2 diabetes |
|
| (viii) Chronic hypertension |
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| (ix) First pregnancy |
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| (x) Pregnancy interval of more than 10 years |
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| (xi) New partner |
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| (xii) Reproductive technologies |
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| (xiii) Family history of PE (mother or sister) |
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| (xiv) Excessive weight gain in pregnancy |
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| (xv) Infection during pregnancy |
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| (xvi) Gestational trophoblastic disease |
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| (xvii) Multiple pregnancies |
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| (xviii) Age 40 years or older |
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| (xix) Ethnicity: Nordic, Black, South Asian, or Pacific Island |
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| (xx) Body mass index of 35 kg/m2 or more at first visit |
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| (xxi) Booking systolic blood pressure >130 mmHg or diastolic blood pressure >80 mmHg |
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| (xxii) Increased prepregnancy triglycerides |
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| (xxiii) Family history of early onset cardiovascular disease |
|
| (xxiv) Lower socioeconomic status |
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| (xxv) Cocaine and methamphetamine use |
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| (xxvi) Nonsmoking |
|
