Table 3.
Effects of ruscogenin on scores for hepatic steatosis and necroinflammation of hamsters.
| RCD-fed | HFD-fed | ||
|---|---|---|---|
| Vehicle | Vehicle | Ruscogenin (3.0 mg/kg/day) | |
| Steatosis (scores 0–4) | 0 ± 0d | 3.1 ± 0.6b | 1.7 ± 0.3b,d |
| Necroinflammation (scores 0–3) | 0 ± 0d | 1.1 ± 0.3b | 0.6 ± 0.2b,c |
The vehicle (distilled water) used to prepare the tested medication solution was given at the same volume. Values (mean ± SEM) were obtained from each group of 8 animals after 8 weeks of the experimental period. a P < 0.05 and b P < 0.01 compared to the values of vehicle-treated RCD-fed hamsters in each group, respectively. c P < 0.05 and d P < 0.01 compared to the values of vehicle-treated HFD-fed hamsters in each group, respectively.