. Author manuscript; available in PMC: 2014 Aug 10.

Published in final edited form as: Anesthesiology. 2009 May;110(5):1086–1091. doi: 10.1097/ALN.0b013e3181a1081d

Table 2.

Baseline Demographics and Physiologic Characteristics of 111 Patients with Severe Pneumonia

	4G/4G and 4G/5G Genotypes	5G/5G Genotype	P Value
n	85	26
Age, yr^*	56.5 ± 19.6	50.6 ± 18.4	0.15
Gender, male (%)	35 (41%)	7 (27%)	0.21
Race
European descent	64 (75%)	20 (77%)	0.15
African descent	5 (6%)	4 (15%)
Asian descent	10 (12%)	0 (0%)
Other	6 (7%)	2 (8%)
Ethnicity, Hispanic (%)	8 (10%)	10 (38%)	0.001
Physiological characteristics^†
APACHE II	20 (15–25)	18 (16–26)	0.56
SAPS II	40 (30–55)	40 (30–47)	0.39
PF ratio	165 (109–212)	145 (119–183)	0.35
Minimum PF ratio < 300	82 (96%)	24 (92%)	0.88
Comorbidities
Sepsis	18 (21%)	5 (19%)	0.8
Septic shock	9 (11%)	3 (12%)	0.9
NYHA category 3 or greater	8 (9%)	0 (0%)	0.1

Mean ± SD.

^†

Median (25th–75th percentile).

APACHE II = acute physiology and chronic health evalution score; NYHA = New York Heart Association; PF = PaO₂/FIO₂; SAPS = simplified acute physiology score.