Table 1.
Pharmacokinetics & positive prevalence results for morphine and codeine in urine samples collected over 32h from 19 subjects receiving two oral poppy seed doses each containing 15.7mg morphine and 3mg codeine separated by 8h.
| Minimum | Maximum | Median | Mean | SD1 | SEM2 | |
|---|---|---|---|---|---|---|
| Morphine peak concentration μg/L | 2413 | 7522 | 5239 | 5248 | 1154 | 288 |
| Codeine peak concentration μg/L | 284 | 1540 | 658 | 718 | 253 | 63 |
| Morphine 2000 μg/L cutoff | ||||||
| Time to first positive h | 1.2 | 12.1 | 6.6 | |||
| Time 2nd dose to last positive h | 2.6 | 18.3 | 12.2 | |||
| Number positive before 2nd dose | 0 | 4 | 1 | |||
| Number positive after 2nd dose | 1 | 6 | 3 | |||
| Morphine 300 μg/L cutoff | ||||||
| Time to first positive h | 0.80 | 2.4 | 1.4 | |||
| Codeine 300 μg/L | ||||||
| Time to first positive h | 1.6 | 19.5 | 6.6 | |||
| Time 2nd dose to last positive h | 2.6 | 14.0 | 8.8 | |||
| Number positive before 2nd dose | 0 | 3 | 1 | |||
| Number positive after 2nd dose | 0 | 5 | 3 |
1
Standard deviation
2
Standard error of the mean