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In vivo collagenolysis mediated by Sca1high ASCs in iWAT and eWAT. (A) The MMP-dependent collagenolysis in iWAT and eWAT was detected with an antibody reactive with MMP-dependent collagen cleavage products (green). Sca1 (red) and nucleus (green) are shown. Focal collagenolysis was increased at Sca1-positive plasma membrane in iWAT, whereas cell-associated collagen cleavage products observed diffusely in eWAT. Scale = 10 μm.
