Table III.
Logistic regression results for associations with major depressive disorder (MDD) among cancer cases, controlling for cancer severity and time since diagnosis.
| Variable | POR | 95% CI | P | |
|---|---|---|---|---|
| Urinary Leakage | ||||
| UI | 1.62 | (1.43, 1.83) | <.0001 | |
| Cancer typea | ||||
| Bladder | 1.20 | (0.92, 1.56) | 0.2 | |
| Breast | 0.95 | (0.77, 1.18) | 0.7 | |
| Colorectal | 1.00 (ref) | -- | -- | |
| Endometrial/Uterine | 0.98 | (0.72, 1.19) | 0.9 | |
| Lung | 1.36 | (1.04, 1.77) | 0.02 | |
| Prostate | 0.96 | (0.78, 1.19) | 0.7 | |
| Demographicsb | ||||
| Age (65–74) | 1.35 | (1.10, 1.64) | 0.001 | |
| Age (75–84) | 1.13 | (0.94, 1.36) | 0.7 | |
| Current Smoker | 1.37 | (1.12, 1.67) | 0.002 | |
| Race (non-white) | 1.04 | (0.89, 1.21) | 0.6 | |
| Gender (male) | 1.02 | (0.82, 1.27) | 0.9 | |
| Marital Status (not married) | 1.54 | (1.35, 1.75) | <.0001 | |
| Education (> high school) | 0.68 | (0.60, 0.80) | <.0001 | |
| Comorbid conditionsb | ||||
| High blood pressure | 1.10 | (0.97, 1.26) | 0.1 | |
| Stroke | 1.38 | (1.15, 1.67) | 0.007 | |
| Chronic lung disease | 1.46 | (1.25, 1.71) | <.0001 | |
| Gastrointestinal problems | 1.93 | (1.54, 2.42) | <.0001 | |
| Diabetes | 0.96 | (0.82, 1.11) | 0.5 | |
| Joint Pain | 1.31 | (1.15, 1.49) | <.0001 | |
| Cardiovascular disease | 1.24 | (1.09, 1.41) | 0.0009 | |
| Time from cancer to survey | ||||
| <2 years | 1.00 (ref) | -- | -- | |
| 2–5 years | 0.86 | (0.72, 1.02) | 0.08 | |
| ≥5 years | 0.83 | (0.72, 0.97) | 0.02 | |
| Cancer Severity | ||||
| In situ/Localized | 1.00 (ref) | -- | -- | |
| Regional/Distant | 1.07 | (0.93, 1.22) | 0.4 | |
| Activities of daily living | ||||
| Difficulty | 2.80 | (2.44, 3.20) | <.0001 |
Colorectal cancer patients within 2 years of treatment, with in situ/localized cancer and those in the referent group of all demographic and comorbid conditions are referent group in model.
Demographics and comorbidities adjustment set (index, referent): age at survey (65–74, 75–84, 85+), smoker (yes, no), race (other, white), gender (male, female), marital status (other, married), education (> high school, ≤ high school), high blood pressure, stroke, chronic lung disease (includes COPD, emphysema or asthma), gastrointestinal problems (including Crone’s, ulcerative colitis, or inflammatory bowel disease) diabetes, joint pain, cardiovascular disease, and difficulty completing one or more activities (getting out of chair, use of toilet, walking, eating, dressing, bathing)