Table 2.

Demographic and clinical data in the two forms of complicated coeliac disease: type A cases, coeliac patients who never responded to a gluten-free diet, type B cases, coeliac patients who initially responded to a gluten-free diet but then relapsed

	Cases type A	Cases type B	p
Number (Females)	59 (32)	28 (23)	0.02*
Age at diagnosis of CD (mean years ± sd)	53 ± 14	47 ± 14	NS**
Age at diagnosis of CCD (mean year ± sd)	54 ± 13	54 ± 13	NS**
Strict adherence to a gluten-free diet	45/59 (83%)	21/28 (75%)	NS*
Years between diagnosis of CD and diagnosis of CCD: median (25th, 75th percentile)	0.3 (0.1, 1.4)	4.9 (3.3, 8.1)	<0.0001***
Mortality	30/59 (51%)	7/28 (25%)	0.03*
Years between diagnosis of CCD and death: median (25th, 75th percentile)	1.0 (0.1, 2.7)	2.3 (0.3, 4.2)	NS***

*Chi² test, **t test, ***Mann–Whitney test, CD = coeliac disease; CCD = complicated coeliac disease; NS = not significant.