Indicator	Link to schizophrenia	Strength of evidence
Pre or perinatal risk factors	Obstetric complications		++
	Low birth weight		++
	In utero infection		++
Developmental trajectory	Motor delay		++
	Social alterations		++
	Cognitive impairments		++
Brain structural alterations	Ventricular enlargement		++
	Grey matter reductions		++
	White matter disruption		+

++=found in meta-analysis; += found in well-controlled studies, ~inconsistent findings