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. 2014 Aug 11;5:383. doi: 10.3389/fpls.2014.00383

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Copyright © 2014 Sasvari, Alatriste Gonzalez and Nagy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functions and subcellular localizations of cell-intrinsic restriction factors inhibiting tombusvirus replication in yeast. Those cellular restriction factors that interact with the tombusvirus replication proteins or the viral RNA are shown in blue. Proteins present in two different subcellular compartments are shown with double-headed arrows. Note that TBSV utilizes the peroxisomal membranes for replication. The scheme also shows the ultrastructure of the tombusvirus VRCs as invaginations in the subcellular membranes.