Table 1.
Baseline characteristics of 26 children undergoing HCT
| Mean +/− SD or N (%) |
|
|---|---|
| Age (y) | 14.9 ± 4.2 |
| Female sex | 14 (54) |
| Nonwhite race | 11 (42) |
| Diagnosis | |
| Acute lymphoblastic leukemia | 7 (27) |
| Acute myelogenous leukemia | 7 (27) |
| Myelodysplastic syndrome | 3 (12) |
| Aplastic anemia | 1 (4) |
| Chronic myelogenous leukemia | 3 (12) |
| Lymphoma | 2 (8) |
| Other | 3 (12) |
| Conditioning regiment | |
| Cyclophosphamide + TBI | 21 (81) |
| Cyclophosphamide + busulfan | 5 (19) |
| Anthropometric measures | |
| Height (cm) | 154.7 ± 19.3 |
| Weight (kg) | 52.6 ± 17.9 |
| BMI (kg/m2) | 21.1 ± 3.63 |
| BMI (z score) | 0.31 ± 0.83 |
| Diet and energy measures | |
| Oral intake at baseline (kcal/day) | 2006 ± 778 |
| REE at baseline (kcal/day) | 1430 ± 282 |
| Laboratory values | |
| Baseline serum CIT (µmol/ | 22.7 ± 12.2 |
| IL-6 | 5.2 ± 5.1 |
| Baseline mucositis score | |
| NCI | |
| NCI = 0 | 23 (88) |
| NCI = 1 | 2 (8) |
| NCI = 2 | 1 (4) |
| WHO | |
| WHO = 0 | 23(88) |
| WHO = 1 | 2 (8) |
| WHO = 2 | 1 (4) |
HCT = hematopoietic cell transplantation; REE = resting energy expenditure; BMI = body mass index; NCI = National Cancer Institute; WHO = World Health Organization, TBI = total body irradiation