Table 6.
Gene variants (SNPs) | Diseases | Population- Ethnic groups | Association | Ref. |
+45 G/T | Obesity | Iranians | NS | [146] |
T2DM | Malaysian | S | [147] | |
T2DM | Greek | NS | [148] | |
MS | Chinese | S | [149] | |
T2DM | Japanese | NS | [150] | |
T2DM | Chinese | S | [151] | |
Non-T2DM | Caucasian Canadians | NS | [152] | |
T2DM | Hispanic Americans | NS | [153] | |
T2DM | French Caucasian | NS | [154] | |
T2DM | Korean | NS | [155] | |
T2DM | Caucasians | S | [154] | |
T2DM | Spanish | NS | [156] | |
IGT | European/Canadian | NS | [157] | |
Non-T2DM | Japanese | NS | [158] | |
Obesity | Swedish | NS | [159] | |
T2DM | Caucasian Italians | NS | [160] | |
T2DM | Caucasian Italians | NS | [161] | |
T2DM | Pima Indians | NS | [162] | |
T2DM | European Caucasians | NS | [163] | |
T2DM | French Caucasians | S | [164] | |
+10211 T/G | T2DM | Asian Indians | S | [165] |
S: Significant; NS: Non-significant; T2DM: Type 2 diabetes; SNPs: Single nucleotide polymorphisms; MS: Metabolic syndrome; IGT: Impaired glucose tolerance.