. Author manuscript; available in PMC: 2014 Aug 11.

Published in final edited form as: Inflamm Bowel Dis. 2013 Jul;19(8):1586–1597. doi: 10.1097/MIB.0b013e318289e17b

Table 2. Vertebral uCT and histomorphometry measures.

Analysis of vertebral trabecular bone histomorphometry and structural parameters.

	Female		Male

	Control	H. hep	Control	H. hep	% Diff

Trabecular
BVF %	28.2 ± 2.5	25.6 ± 2.7	31.8 ± 3.9	17.0 ± 3.0 ^*^#	46 ↓
BMC (mg)	0.52 ± 0.02	0.52 ± 0.04	0.53 ± 0.02	0.44 ± 0.02^#	17 ↓
BMD (mg/cc)	260 ± 16	251 ± 14	227 ± 10	197 ± 10 ^*
Tb.N (1/mm)	6.04 ± 0.30	5.65 ± 0.37	7.16 ± 0.42	5.18 ± 052^#	28 ↓
Tb.Th (µm)	46.3 ± 2.2	45.0 ± 2.4	43.9 ± 3.1	32.0 ± 2.5 ^*^#	27 ↓
Tb.Sp (µm)	121 ± 12	135 ± 14	97 ± 11	166 ± 20^#	71 ↑
Histomorphometry
Osteoblast %	12.2 ± 0.6	11.2 ± 0.8	8.7 ± 0.8 ^*	7.0 ± 0.9 ^*
Osteoclast %	5.6 ± 1.0	8.7 ± 1.0	3.4 ± 0.4	5.2 ± 1.2
MAR (µm/day)	1.41 ± 0.12	1.13 ± 0.07	1.19 ± 0.06	1.34 ± 16
BFR (µm³/µm²/day)	0.19 ± 0.05	0.20 ± 0.04	0.14 ± 0.01	0.15 ± 0.04

The L3 vertebrae were examined. BV/TV, bone volume fraction; BMC, bone mineral content; BMD, bone mineral density; Tb.N., trabecular number; Tb. Th., trabecular thickness; Tb. Sp., trabecular spacing; Tt. Ar., total area; Ct. Ar., cortical area; Ma. Ar., marrow area; Ct. Ar./Tt. Ar., cortical area fraction; Ct. Th., cortical thickness; Inner P, inner perimeter; Outer P, outer perimeter. Values are averages SE;

p<0.05 compared to female controls;

p<0.05 compared to corresponding gender control.