Figure 4.
Sulindac and atorvastatin do not enhance zinc finger protein 36 (Zfp36) expression in 3T3-L1 adipocytes. Western blot analysis of Zfp36 expression in 3T3-L1 adipocytes grown in serum-free medium with the following 6 h treatments: vehicle control, dexamethasone (Dex, 1 μmol/l), forskolin (10 μmol/l), the nonsteroidal anti-inflammatory drug (NSAID) sulindac (100 μmol/l), and the lipid-lowering statin drug atorvastatin (5 μmol/l). Quantitative image analysis indicating Zfp36 expression relative to control cells, normalized to actin, is shown. Data are representative of three independent experiments.