Table 3.
Medication Treatment Compliance
| Variable | Varenicline (n=86) | Bupropion (n=102) | Placebo (N=106) | Total (N=294) |
|---|---|---|---|---|
|
| ||||
| % (N) | % (N) | % (N) | % (N) | |
| Retained For 12 Week Treatment | 86 (74) | 87.3 (89) | 84 (89) | 86 (252) |
| Stopped Medication-Total Subjects | 20.9 (18) | 22.5 (23) | 25.5 (27) | 23.1 (68) |
| * Stopped Medication & Continued in Counseling | 33 (6) | 43 (10) | 37 (10) | 38 (26) |
| * Stopped Medication & Dropped | 67 (12) | 57 (13) | 63 (17) | 62 (42) |
| Took ≥ 80% of Medication Dose | 72 (62) | 78 (102) | 75 (79) | 75 (220) |
| Mean Percent of Total Pills Taken1 | ||||
| All Subjects2 | 81 | 83 | 83 | 82 |
| Treatment Completers Only3 | 92 | 94 | 93 | 93 |
| Treatment Non-completers Only4 | 38 | 40 | 49 | 42 |
*
Percent of those who stopped medication
1
Total Pills Assigned-Total Pills Returned/Total Pills Assigned. In the case of premature discontinuation of medication, the total pills assigned and returned would be the same and prorated from the time the medication was discontinued through week 12.
2
Includes those that stopped medication and remained for counseling plus those that withdrew/failed to return during the 12 week treatment.
3
Includes all smokers who did not prematurely discontinue medication
4
Includes only those smokers who discontinue medication/withdraw sometime during treatment