Figure 5. Comparison of RTA-G12 and RTA-A7 interfaces.
The super positioned Cα-traces of RTA in complex with VHH G12 (green-cyan, respectively) and VHH A7 (gray-gray, respectively). The inset illustrates the 3 additional main-chain hydrogen bonds that occur at the interface between RTA and VHH G12 that are absent between RTA and VHH A7. Hydrogen bonds are drawn as red dashes. The key residue in VHH A7, Pro 106, is labeled in gray.