Fig. 7.

Increase in CYP1(A/B) enzymatic activity was detected after B[a]P exposure using the EROD activity assay. Statistically significant increases were detected after 24 h of exposure to 0.1 μM B[a]P and 1 μM B[a]P alone. Under co-exposure conditions with Cd and B[a]P significant increases in enzymatic activity were detected at 1 μM Cd × 0.1 μM B[a]P and 1 μM Cd × 1 μM B[a]P. Points represent mean (n = 3) pg resorufin/mg protein ± SEM and expressed as percent of the DMSO control group for each respective time point, # indicates significant difference from the DMSO control group at each respective time point, p < 0.05.