| Skaane et al,6 2013 |
Interim analysis of prospective reader, modality balanced |
12,631 (expect 18,000) |
15% decrease (P<.001) |
27% increase |
40% increase in invasive cancer detection (P<.001) |
| Rose et al,18 2013 |
Prospective clinical practice comparing DBT with years prior of DM |
9256 DBT screens compared with the prior 2 y of DM |
DBT recall 5.3% compared with DM-only recall 8.7% (−39.5%; P<.001) |
DBT cancer detection rate 5.83/1000 compared with DM rate of 3.6/1000 (P = .003) |
Additional cancers mostly invasive |
| Haas et al,19 2013 |
Prospective clinical practice, indirect comparison of patient from one practice with DBT with another practice without DBT |
Practice of 1602 DBT screens vs practice of 4178 DM |
DBT recall 7% compared with DM-only recall 10.9% (P<.01) |
DBT cancer detection rate 5.6/1000 vs DM rate of 3.4/1000 (−35.8%; P = .24) |
Reduction in recall with DBT largest in patients younger than 50 and/or dense breasts |
| Conant et al,20 2013 RSNA |
Clinical practice, prospective comparing DBT with prior year of DM, stable readers |
15,633 DBT screens compared with prior year of 10,753 DM |
15% reduction in recall (P<.001; odds ratio = .80) |
Trend of increased cancer detection from 4.4 pre-DBT to 5.48 with DBT (P = .26) |
There was a statistical significant increase in cancer detected with DBT in women <50 years |
