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Association of deletions and duplications with melanoma subtype.
| Frequency with del/dup | ||||
|---|---|---|---|---|
| WT, n=6 | NRAS mutant, n=8 | BRAF mutant, n=23 | Total, n=37 | |
| CDKN2A, del | 3 (50%) | 4 (50%) | 15 (64%) | 22 (58%) |
| PTEN, del | 1 (17%) | 1 (12%) | 12 (54%)* | 14 (38%) |
| BRAF, dup | 1 (17%) | 3 (38%) | 8 (35%) | 12 (31%) |
| MITF, dup | 0 | 2 (25%) | 9 (39%) | 11 (28%) |
Del, deletion; dup, duplication;
P=0.05, BRAF mutant vs NRAS mutant
