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. 2014 Aug 5;5(4):e01119-14. doi: 10.1128/mBio.01119-14

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Copyright © 2014 Holmblat et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.

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FIG 2 — Genomic features of recombinant viruses. The different types of recombinants generated (homologous H and nonhomologous NH-1, NH-2, and NH-Δ) are illustrated. All the recombinants shown in this schematic diagram have a recombination site in the 2A coding region (solid triangle). The recombination site and the homologous duplicated sequences are enlarged for NH-1, NH-2, and NH-Δ recombinants. Vertical arrows indicate the natural VP1/2A cotranslational cleavage site of the viral polyprotein. NH-2 and NH-1 recombinants have duplicated homologous sequences (indicated by horizontal double-headed arrows) flanking the recombination site. NH-2 recombinants also display duplication of the natural VP1/2A cleavage site. NH-Δ recombinants have a short deletion.