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. Author manuscript; available in PMC: 2014 Aug 11.
Published in final edited form as: Mol Cancer Ther. 2012 Jun 6;11(8):1661–1671. doi: 10.1158/1535-7163.MCT-12-0072

Figure 5. Combined OGX-427 plus chloroquine delays PC-3 xenograft growth in vivo.

Figure 5

A, PC-3 cells were inoculated s.c. and when tumors reached 100mm3, mice were treated with scrambled (ScrB) control+PBS, ScrB+chloroquine (CQ), OGX-427+PBS or OGX-427+CQ as described in Materials and Methods. Each data point represents the mean tumor volume in each group containing 8 mice ± SEM. *, differ from ScrB+PBS, ScrB+CQ or OGX-427+PBS treatment group (P<0.05). B, tumors were collected after 49 days. Hsp27, Ki-67 and TUNEL were evaluated by immunohistochemical analysis (original magnification: x200).