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. Author manuscript; available in PMC: 2015 Jul 29.
Published in final edited form as: Mol Biosyst. 2014 Jul 29;10(9):2347–2357. doi: 10.1039/c4mb00263f

Fig. 5.

Fig. 5

Model-predicted restoration of normal thrombin and fibrin generation in diluted plasma by clotting factor supplementation. “Fg” stands for supplementation with fibrinogen, “PCC” denotes supplementation with PCC-AT (a combination of the factors II, IX, X, and antithrombin), and “Fg/PCC” denotes simultaneous supplementation with fibrinogen and PCC-AT. A: Clotting was initiated with 2 pM TF. B: Clotting was initiated with 5 pM TF. C: Clotting was initiated with 10 pM TF. Here, the blue and red lines for fibrin generation practically coincide, as do the orange and red lines for thrombin generation.