Table 4.
Water consumption (mL; mean ± SE; n = 4 cages) and plasma antibiotic concentration (ng/mL; mean ± SE)
| Consumptiona | Plasma antibiotic concentrationb at | ||||
| Antibiotic | Control water | Antibiotic water | 0700 | 1900 | 0100 |
| Enrofloxacin | 9.7 ± 0.8 | 11.4 ± 0.3c | 112.2 ± 11.7 | 140.1 ± 10.4 | 117.5 ± 16.9 |
| Doxycycline | 9.3 ± 0.3 | 10.1 ± 0.9 | 56.6 ± 12.5 | 42.9 ± 7.8 | not tested |
| Amoxicillin | 9.3 ± 0.4 | 8.8 ± 0.8 | 299.2 ± 64.1 | 275.2 ± 50.2 | not tested |
| TMS | 10.1 ± 1.3 | 11.2 ± 1.5 | 5.7 ± 2.3 | 5.9 ± 1.2 | not tested |
a
Consumption data represent 2 mice per cage.
b
n = 8 mice per antibiotic, except for the 0100 enrofloxacin sample (n = 4).
c
Value significantly (P < 0.05) different from that for consumption of control water.