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. 2014 Aug 11;9(8):e103045. doi: 10.1371/journal.pone.0103045

Table 4. Performance of different image reconstruction algorithms during mechanical ventilation with constant tidal volume and variable end-expiratory pressure and O2 fraction.

Expected finding Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic Inline graphic
VInline graphic is independent of Peep
VInline graphic Inline graphic  =  VInline graphic Inline graphic 0.224 0.268 0.512 0.838 0.024* 0.008* 0.000* 0.225 0.247 0.815 0.018* 0.044*
VInline graphic Inline graphic  =  VInline graphic Inline graphic 0.022* 0.027* 0.090 0.247 0.008* 0.014* 0.000* 0.026* 0.030* 0.245 0.010* 0.013*
VInline graphic is independent of FI o 2
VInline graphic Inline graphic  =  VInline graphic Inline graphic 0.010* 0.009* 0.000* 0.010* 0.033* 0.025* 0.000* 0.009* 0.035* 0.030* 0.010* 0.004*
VInline graphic Inline graphic  =  VInline graphic Inline graphic 0.002* 0.002* 0.010* 0.005* 0.001* 0.001* 0.000* 0.002* 0.001* 0.042* 0.002* 0.001*
VInline graphic is reproducible
VInline graphic Inline graphic  =  VInline graphic Inline graphic 0.003* 0.003* 0.001* 0.012* 0.002* 0.001* 0.000* 0.002* 0.003* 0.007* 0.001* 0.001*
VInline graphic Inline graphic  =  VInline graphic Inline graphic 0.000* 0.000* 0.001* 0.002* 0.001* 0.001* 0.000* 0.000* 0.001* 0.002* 0.001* 0.000*
CoV is Peep dependent
CoVInline graphic Inline graphic CoVInline graphic 0.088 0.088 0.136 0.114 0.060 0.037* 0.121 0.085 0.075 0.083 0.043* 0.064
CoVInline graphic Inline graphic CoVInline graphic 0.034* 0.033* 0.044* 0.052 0.026* 0.017* 0.053 0.033* 0.035* 0.022* 0.019* 0.023*
CoV is FI o 2 dependent
CoVInline graphic Inline graphic CoVInline graphic 0.012* 0.012* 0.020* 0.020* 0.010* 0.010* 0.035* 0.011* 0.016* 0.009* 0.011* 0.010*
CoVInline graphic Inline graphic CoVInline graphic 0.659 0.679 0.689 0.713 0.586 0.639 0.751 0.662 0.664 0.735 0.604 0.683
CoV is reproducible
CoVInline graphic  =  CoVInline graphic 0.059 0.064 0.238 0.013* 0.061 0.023* 0.009* 0.065 0.107 0.026* 0.032* 0.007*
CoVInline graphic  =  CoVInline graphic 0.009* 0.009* 0.010* 0.000* 0.028* 0.016* 0.001* 0.010* 0.042* 0.006* 0.017* 0.002*

The expected physiological findings regarding the magnitude and distribution of ventilation are used as reference states. Inline graphic-values of the Student's Inline graphic-test are reported. For each test, Inline graphic (the number of animals).

E, Measures by EIT; VInline graphic, tidal volume; Peep (P), positive end-expiratory pressure; ZEEP (Z), zero end-expiratory pressure; FI o 2, fraction of OInline graphic in inspired gas; 21, FI o 2 equal to 21%; 100, FI o 2 equal to 100%; indices 1 and 2 identify the first and the second measurements at identical ZEEP or Peep levels; CoV, center of ventilation; Inline graphic hypothesis confirmed at Inline graphic.