Table 4.
Results for overall and sub-group analysis according to type of study and treatment
|
Outcomes |
Estimates (95% CI) |
|
|||
|---|---|---|---|---|---|
| Combined | RCTs | Pre-post studies | Preventive | Therapeutic | |
|
Chagas | |||||
| Peri-domiciliary Infestation Rate |
0.77 [0.53, 1.14] |
0.94 [0.67, 1.32] |
0.17 [0.06, 0.48] |
0.77 [0.53, 1.14] |
No studies |
| 8 datasets, 3 studies |
4 datasets, 1 study |
4 datasets, 2 studies |
8 datasets, 3 studies |
||
| Domiciliary Infestation Rate |
0.32 [0.19, 0.55] |
No studies |
0.32 [0.19, 0.55] |
0.32 [0.19, 0.55] |
No studies |
| 4 datasets, 2 studies |
|
4 datasets, 2 studies |
4 datasets, 2 studies |
||
| Chagas Serology Rate (RR) |
0.78 [0.61, 0.98] |
No studies |
0.78 [0.61, 0.98] |
0.78 [0.61, 0.98] |
No studies |
| 4 datasets, 2 studies |
4 datasets, 2 studies |
4 datasets, 2 studies |
|||
|
Dengue | |||||
| House Index |
0.84 [0.81, 0.88] |
No studies |
0.84 [0.81, 0.88] |
0.84 [0.81, 0.88] |
No studies |
| 9 datasets, 9 studies |
9 datasets, 9 studies |
9 datasets, 9 studies |
|||
| Ovitrap Index |
0.77 [0.64, 0.92] |
No studies |
0.77 [0.64, 0.92] |
0.77 [0.64, 0.92] |
No studies |
| 5 datasets, 3 studies |
5 datasets, 3 studies |
5 datasets, 3 studies |
|||
| Mean Bretreau Index (SMD) |
−0.04 [−0.28, 0.19] |
−0.04 [−0.28, 0.19] |
No studies |
−0.04 [−0.28, 0.19] |
No studies |
| 5 datasets, 2 studies |
5 datasets, 2 studies |
5 datasets, 2 studies |
|||
| Dengue Positive Serostatus |
0.31 [0.18, 0.53] |
0.33 [0.18, 0.60] |
0.14 [0.01, 1.62] |
0.31 [0.18, 0.53] |
No studies |
| 4 datasets, 4 studies |
2 datasets, 2 studies |
2 datasets, 2 studies |
4 datasets, 4 studies |
||
|
Trachoma | |||||
| Active Trachoma All Age Groups |
0.24 [0.21, 0.26] |
0.72 [0.59, 0.88] |
0.15 [0.14, 0.17] |
0.72 [0.59, 0.88] |
0.15 [0.14, 0.17] |
| 6 datasets, 3 studies |
2 datasets, 1 study |
4 datasets, 2 studies |
2 datasets, 1 study |
4 datasets, 2 studies |
|
| Active Trachoma in Children |
0.67 [0.64, 0.69] |
0.86 [0.83, 0.90] |
0.38 [0.36, 0.40] |
0.77 [0.74, 0.79] |
0.32 [0.29, 0.35] |
| 20 datasets, 14 studies |
6 datasets, 4 studies |
14 datasets, 9 studies |
13 datasets, 8 studies |
7 datasets, 6 studies |
|
| Chlamydia Trachomatic infection- All Age Groups |
0.29 [0.27, 0.32] |
0.28 [0.25, 0.31] |
0.32 [0.27, 0.37] |
0.28 [0.25, 0.31] |
0.36 [0.29, 0.46] |
| 10 datasets, 6 studies |
5 datasets, 3 studies |
5 datasets, 3 studies |
7 datasets from 5 studies |
3 datasets, 1 studies |
|
| Chlamydia Trachomatic infection in Children |
0.21 [0.18, 0.24] |
0.15 [0.13, 0.19] |
0.42 [0.31, 0.55] |
0.21 [0.18, 0.24] |
No studies |
| 9 datasets, 7 studies |
6 datasets, 4 studies |
3 datasets, 3 studies |
9 datasets, 7 studies |
||
|
Leishmaniasis | |||||
| Incidence Cutaneous Leishmaniasis |
0.42 [0.36, 0.49] |
0.40 [0.32, 0.51] |
0.43 [0.35, 0.53] |
0.42 [0.36, 0.49] |
No studies |
| 9 datasets, 5 studies |
5 datasets, 3 studies |
4 datasets, 2 studies |
9 datasets, 5 studies |
||
| Incidence of Visceral Leishmaniasis |
0.93 [0.83, 1.04] |
0.97 [0.84, 1.12] |
0.87 [0.73, 1.04] |
0.93 [0.83, 1.04] |
No studies |
| 4 datasets, 4 studies |
2 datasets, 2 studies |
2 datasets, 2 studies |
4 datasets, 4 studies |
||
| Cure Rate for Cutaneous Leishmaniasis (RR) |
0.92 [0.88, 0.96] |
No studies |
0.92 [0.88, 0.96] |
No studies |
0.92 [0.88, 0.96] |
| 2 datasets, 2 studies |
2 datasets, 2 studies |
2 datasets, 2 studies |
|||
|
Leprosy | |||||
| Leprosy Incidence |
0.32 [0.30, 0.34] |
0.67 [0.49, 0.92] |
0.31 [0.29, 0.33] |
0.32 [0.30, 0.34] |
No studies |
| 8 datasets, 5 studies |
1 datasets, 1 studies |
7 datasets, 4 studies |
8 datasets, 5 studies |
||
| Leprosy detection rate |
1.11 [1.02, 1.21] |
No studies |
1.11 [1.02, 1.21] |
1.11 [1.02, 1.21] |
No studies |
| 2 datasets, 2 studies | 2 datasets, 2 studies | 2 datasets, 2 studies | |||
Estimates in bold represents statistical significance.