Table 1. List of the B. pseudomallei genes that have >2SD fold change in expression (in vivo/in vitro).
Locus Tag | Gene Symbol (NCBI) | Gene description (NCBI) | Fold Change | |||||
Spleen | Lung | Liver | ||||||
BALB/c | C57BL/6 | BALB/c | C57BL/6 | BALB/c | C57BL/6 | |||
BPSL0226 | fliJ | Flagella fliJ protein | *6.33 | *4.65 | ND | ND | 1.91 | 3.39 |
BPSL0274 | flgF | Flagella basal body rod protein FlgF | *4.52 | 1.81 | 1.19 | 1.36 | 1.01 | 1.45 |
BPSL0029 | fliO | Flagella protein | 2.21 | 3.31 | 3.61 | 1.91 | *13.55 | 2.7 |
BPSL0272 | flgD | Flagella basal body rod modification protein | 2.9 | 1.4 | 0.77 | *9.58 | 0.79 | 1.81 |
BPSL0277 | flgI | Flagella basal body P-ring protein | 1.0 | *8.26 | 2.23 | *5.72 | 2.65 | 1.09 |
BPSL0808 | Peptidase | 1.2 | 1.82 | 1.5 | *7.12 | 1.57 | 0.83 | |
BPSL1505 | rpoS | RNA polymerase sigma factor RpoS | 1.42 | 1.56 | *4.03 | 3.63 | 2.07 | 1.07 |
BPSL1819 | Fimbriae-assembly-like protein | 2.64 | 2.09 | 1.83 | *4.43 | 2.55 | 2.6 | |
BPSL1820 | Fimbriae assembly-like protein | 3.15 | 1.76 | 0.97 | 1.85 | *4 | 3.27 | |
BPSL1902 | Hypothetical protein | 2.52 | 1.42 | *3.71 | 2.36 | 2.05 | 1.28 | |
BPSL2403 | plcN | Non-hemolytic phospholipase C | 0.58 | *7.9 | 0.9 | 2.21 | 3.4 | 0.43 |
BPSL2686 | rmlB | dTDP-glucose 4,6-dehydratase | *3.9 | 1.04 | 2.28 | 2.54 | 1.57 | 1.18 |
BPSL3099 | Outer membrane protein | 0.84 | 0.88 | 0.98 | 0.98 | *4.9 | 0.77 | |
BPSL3172 | Hypothetical protein | 1.1 | 1.5 | 2.6 | *4.3 | 0.78 | 2.74 | |
BPSL3294 | flhA | Flagella biosynthesis protein FlhA | 0.68 | 0.66 | 0.36 | 1.28 | *4.66 | *3.89 |
BPSL3304 | tsr | Methyl-accepting chemotaxis protein I | *3.91 | 2.49 | 0.78 | *13.9 | 1.93 | 3.49 |
BPSS0029 | Transport-related membrane protein | 2.86 | 1.38 | 0.78 | *6.12 | 0.67 | *3.82 | |
BPSS0417 | Hypothetical protein | 1.23 | 2.74 | 0.98 | *6.15 | 1.24 | *3.94 | |
BPSS0520 | Hypothetical protein | 1.51 | 0.84 | 0.65 | 1.72 | 1.31 | *6.03 | |
BPSS0524 | Hypothetical protein | 1 | *4.29 | 2.19 | 2.23 | 2.31 | 1.14 | |
BPSS0860 | Flagella hook-associated protein | 1.41 | 2.14 | 1.29 | *3.92 | 2.44 | 1.86 | |
BPSS0989 | Hypothetical protein | 2.94 | *3.75 | 1.71 | 2.46 | 3.09 | 1.65 | |
BPSS1264 | Hypothetical protein | 2.62 | 2.35 | *9.47 | 1.7 | *94.6 | 6.24 | |
BPSS1405 | sctS | Type III secretion-associated protein | *3.92 | 2.16 | 1.47 | 2.08 | 1.93 | 3.49 |
BPSS1507 | ttssI | Hypothetical protein | 2.6 | *3.79 | 0.75 | 2.24 | 1.13 | *4.0 |
BPSS1512 | tssM | Hypothetical protein | 1.9 | 2.07 | 1.24 | *7.36 | *7.4 | 2.6 |
BPSS1521 | bprD | Hypothetical protein | *8.8 | *7.17 | 3.49 | *21.0 | 3.46 | *18.6 |
BPSS1524 | bopA | Intercellular spread protein | 0.45 | 0.52 | *10.4 | 0.72 | 2.23 | 0.82 |
BPSS1531 | bipC | Cell invasion protein | *3.89 | 3.35 | *3.92 | 3.63 | 3.15 | 1.75 |
BPSS1533 | bicA | Surface presentation of antigens protein | 3.08 | *4.6 | 2.51 | 2.66 | 2.47 | 2.527 |
BPSS1538 | bsaV | Surface presentation of antigens protein | 1.1 | 1.52 | *3.82 | 1.05 | *4.45 | 1.26 |
BPSS1543 | bsaQ | Type III secretion system protein | 1.25 | *24.05 | 2.17 | *8.19 | 2.63 | 0.83 |
BPSS1833 | udg2 | UDP-glucose 6-dehydrogenase 2 | *4.17 | 1.15 | 1.84 | 1.9 | 1.44 | 1.07 |
BPSS1875 | Chemotaxis-related protein | *3.84 | *4.56 | 2.04 | *7.54 | 1.4 | 3.49 | |
BPSS2095 | Hypothetical protein | 2.45 | 1.59 | 0.42 | *4.83 | 1.14 | 2.34 | |
BPSS2103 | Hypothetical protein | *6.74 | 1.65 | 3.5 | *4.2 | *4.0 | 2.28 |
* Expression level change >2SD in the organs of mice and ND = no data.