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. 2014 Aug 11;9(8):e104757. doi: 10.1371/journal.pone.0104757

Figure 4. Distribution of differentially methylated sites in CFS according to GO clusters and functional relevance.

Figure 4

Relative proportions of hyper- and hypo-methylated CpG sites between CFS patients and healthy control subjects for genes associated with the immune cell regulation cluster group (immune GO) compared to all four GO term cluster groups (all GO). Results are shown for each genic region, consisting of promoter regions within 1500 bp and 200 bp of the transcription start sites (TSS), gene regulatory elements (regulatory: TSS1500, TSS200, 5′ UTR, 3′ UTR), the coding regions of genes (gene body), as well as all regions combined (total: regulatory, gene body). * = p<0.0125, Pearson Chi-Squared Test.