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. 2014 Aug 11;9(8):e104825. doi: 10.1371/journal.pone.0104825

Table 3. Linear regression model of factors associated with serum 25-hydroxyvitamin D (nmol/L), 1,25-dihydroxyvitamin D (pmol/L) and parathyroid hormone concentrations (ng/L) among Thai schoolchildren aged 6–13 y1.

Unadjusted Adjusted/final2 , 3
Variable n Estimates 95% CI P n Estimates 95% CI P
For 25(OH)D 525
BMI 525 0.99 0.98, 1.00 0.021 0.997 0.987, 1.01 0.515
Sex (male) 526 1.19 1.14, 1.23 <0.001 1.19 4 1.14, 1.23 <0.001
Age, y 526 0.98 0.96, 0.99 0.010
Age, y for boys 1.00 0.98, 1.02 0.895
Age, y for girls 0.96 0.94, 0.97 0.001
Sex × Age interaction <0.001
Height-for-age Z score 526 0.97 0.94, 0.99 0.017 0.98 0.96, 0.99 0.006
For 1,25(OH)2D 510
BMI 518 1.03 1.00, 1.06 0.028 1.11 1.04, 1.18 0.004
BMI-squared 0.996 0.994, 0.999 0.009 0.997 0.996, 0.999 0.004
Sex (male) 519 0.86 0.83, 0.89 <0.001 0.86 0.82, 0.90 <0.001
Age, y 519 1.02 0.99, 1.05 0.232 1.02 0.99, 1.04 0.17
Height-for-age Z score 519 1.07 1.05, 1.110 <0.001 1.07 1.04, 1.11 0.001
log 25OHD 512 0.91 0.76, 1.08 0.235 1.12 0.95, 1.33 0.153
For PTH 502
BMI 514 1.02 0.99, 1.04 0.196 0.98 0.96, 1.02 0.365
Sex (male) 515 0.80 0.74, 0.87 <0.001 0.91 0.82, 1.02 0.097
Age, y 515 1.04 1.01, 1.07 0.008 1.03 0.999, 1.07 0.055
Age-squared 1.02 1.00, 1.04 0.037 1.02 1.00, 1.03 0.049
Height-for-age Z score 515 1.10 1.03, 1.18 0.012 1.08 1.02, 1.14 0.016
log 25OHD 509 0.50 0.43, 0.57 <0.001 0.61 0.49, 0.74 <0.001
log 1,25(OH)2D 509 1.34 1.09, 1.64 0.012 1.18 0.99, 1.40 0.06
1

Effect sizes are ratios of geometric means, accompanied by 95% CIs and P-values.

2

Adjusted for variables with P≤0.25 in univariate analysis.

3

R2 of the whole model for 25OHD: 0.24; for 1,25(OH)2D: 0.13; for PTH: 0.20.

4

At the mean age (9.9 y).