Table 3. Linear regression model of factors associated with serum 25-hydroxyvitamin D (nmol/L), 1,25-dihydroxyvitamin D (pmol/L) and parathyroid hormone concentrations (ng/L) among Thai schoolchildren aged 6–13 y1.
Unadjusted | Adjusted/final2 , 3 | |||||||
Variable | n | Estimates | 95% CI | P | n | Estimates | 95% CI | P |
For 25(OH)D | 525 | |||||||
BMI | 525 | 0.99 | 0.98, 1.00 | 0.021 | 0.997 | 0.987, 1.01 | 0.515 | |
Sex (male) | 526 | 1.19 | 1.14, 1.23 | <0.001 | 1.19 4 | 1.14, 1.23 | <0.001 | |
Age, y | 526 | 0.98 | 0.96, 0.99 | 0.010 | ||||
Age, y for boys | 1.00 | 0.98, 1.02 | 0.895 | |||||
Age, y for girls | 0.96 | 0.94, 0.97 | 0.001 | |||||
Sex × Age interaction | <0.001 | |||||||
Height-for-age Z score | 526 | 0.97 | 0.94, 0.99 | 0.017 | 0.98 | 0.96, 0.99 | 0.006 | |
For 1,25(OH)2D | 510 | |||||||
BMI | 518 | 1.03 | 1.00, 1.06 | 0.028 | 1.11 | 1.04, 1.18 | 0.004 | |
BMI-squared | 0.996 | 0.994, 0.999 | 0.009 | 0.997 | 0.996, 0.999 | 0.004 | ||
Sex (male) | 519 | 0.86 | 0.83, 0.89 | <0.001 | 0.86 | 0.82, 0.90 | <0.001 | |
Age, y | 519 | 1.02 | 0.99, 1.05 | 0.232 | 1.02 | 0.99, 1.04 | 0.17 | |
Height-for-age Z score | 519 | 1.07 | 1.05, 1.110 | <0.001 | 1.07 | 1.04, 1.11 | 0.001 | |
log 25OHD | 512 | 0.91 | 0.76, 1.08 | 0.235 | 1.12 | 0.95, 1.33 | 0.153 | |
For PTH | 502 | |||||||
BMI | 514 | 1.02 | 0.99, 1.04 | 0.196 | 0.98 | 0.96, 1.02 | 0.365 | |
Sex (male) | 515 | 0.80 | 0.74, 0.87 | <0.001 | 0.91 | 0.82, 1.02 | 0.097 | |
Age, y | 515 | 1.04 | 1.01, 1.07 | 0.008 | 1.03 | 0.999, 1.07 | 0.055 | |
Age-squared | 1.02 | 1.00, 1.04 | 0.037 | 1.02 | 1.00, 1.03 | 0.049 | ||
Height-for-age Z score | 515 | 1.10 | 1.03, 1.18 | 0.012 | 1.08 | 1.02, 1.14 | 0.016 | |
log 25OHD | 509 | 0.50 | 0.43, 0.57 | <0.001 | 0.61 | 0.49, 0.74 | <0.001 | |
log 1,25(OH)2D | 509 | 1.34 | 1.09, 1.64 | 0.012 | 1.18 | 0.99, 1.40 | 0.06 |
Effect sizes are ratios of geometric means, accompanied by 95% CIs and P-values.
Adjusted for variables with P≤0.25 in univariate analysis.
R2 of the whole model for 25OHD: 0.24; for 1,25(OH)2D: 0.13; for PTH: 0.20.
At the mean age (9.9 y).