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. 2014 Aug 11;9(8):e104402. doi: 10.1371/journal.pone.0104402

Table 3. Subgroup analysis on primary diseases.

Short-term treatment Long-term treatment
RR (95% CI) P for interaction RR (95% CI) P for interaction
All stroke
Prior stroke/TIA 0.69 (0.58–0.81) 0.12 0.84 (0.71–0.99) 0.58
Other vascular event/risk 0.83 (0.70–0.99) 0.79 (0.70–0.89)
Ischemic stroke
Prior stroke/TIA 0.68 (0.57–0.81) 0.12 0.78 (0.66–0.93) 0.78
Other vascular event/risk 0.84 (0.69–1.04) 0.76 (0.67–0.86)
Hemorrhagic stroke
Prior stroke/TIA 1.00 (0.38–2.66) 0.97 1.56 (0.86–2.84) 0.43
Other vascular event/risk 0.98 (0.69–1.39) 1.15 (0.73–1.84)
Major bleeding
Prior stroke/TIA 0.88 (0.32–2.41) 0.64 1.70 (1.31–2.22) 0.31
Other vascular event/risk 1.12 (0.92–1.37) 1.47 (1.31–1.64)
Intracranial bleeding
Prior stroke/TIA NA NA 1.56 (0.83–2.95) 0.66
Other vascular event/risk 0.92 (0.66–1.30) 1.87 (1.19–2.93)

CI: confidence interval; NA: not available; RR; relative risk; TIA: transient ischemic attack.