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. 2014 Aug 11;9(8):e104094. doi: 10.1371/journal.pone.0104094

Table 2. Inhibitor Ki values with AA from Dixon replots.a .

Compound Ki Ki
MLS000545091 0.9 (0.4) 9.9 (0.7)
MLS000536924 2.5 (0.5) n/ab
a

All assays were done in triplicate.

The Ki was determined from the slope (Km/Vmax) replot at varying inhibitor concentration. The Ki′ was determined similarly from the y-intercept (1/Vmax) replot.

b

The y-intercept did not vary with increasing inhibitor, indicating a competitive inhibitor.

The inhibition constants are in units of micromolar, with error in parentheses.