Table 1. Clinical data of patients with positive SLNs from MSKCC, SOC and PKUPH.
MSKCC | SOC | PKUPH | ||||||
Total patients | 702 | 285 | 120 | |||||
Patient and Tumor Characteristics | n | % | n | % | Mean | n | % | Mean |
Age(years) | 55.8 | 52.53 | ||||||
≤50 | 290 | 41.3 | 59 | 49.2 | ||||
>50 | 412 | 58.7 | 61 | 50.8 | ||||
Tumor size (cm) | ||||||||
≤1.0 | 155 | 22.1 | 31 | 10.9 | 25 | 20.8 | ||
>1.0 to ≤2.0 | 312 | 44.4 | 125 | 43.9 | 64 | 53.3 | ||
>2.0 to ≤3.0 | 154 | 21.9 | 129 | 45.2 | 22 | 18.3 | ||
>3.0 | 81 | 11.6 | 9 | 7.5 | ||||
Tumor type | ||||||||
Ductal | 618 | 88.0 | 246 | 86.3 | 73 | 60.8 | ||
Lobular | 84 | 12.0 | 27 | 9.5 | 6 | 0.1 | ||
Mixed | 11 | 3.9 | 38 | 31.7 | ||||
Special type | 1 | 0.4 | 3 | 2.5 | ||||
Nuclear grade | ||||||||
I | 22 | 3.1 | 91 | 31.9 | 13 | 10.8 | ||
II | 321 | 45.7 | 120 | 42.1 | 74 | 61.7 | ||
III | 275 | 39.2 | 74 | 26.0 | 27 | 22.5 | ||
Lobular | 84 | 12.0 | 6 | 5.0 | ||||
LVI | ||||||||
Yes | 284 | 40.5 | 95 | 33.3 | 14 | 11.7 | ||
No | 418 | 59.5 | 118 | 41.4 | 106 | 88.3 | ||
Unknown | 72 | 25.3 | ||||||
Multifocality | ||||||||
Yes | 197 | 28.1 | 9 | 7.5 | ||||
No | 505 | 71.9 | 111 | 92.5 | ||||
ER status | ||||||||
+ | 567 | 80.8 | 194 | 68.1 | 101 | 84.2 | ||
− | 135 | 19.2 | 38 | 13.3 | 19 | 15.8 | ||
Unknown | 53 | 18.6 | ||||||
Method of SLN detection | ||||||||
Frozen section | 463 | 66.0 | 99 | 82.5 | ||||
Routine HE | 65 | 9.3 | 220 | 77.2 | 21 | 17.5 | ||
Serial HE | 78 | 11.1 | ||||||
IHC | 63 | 9.0 | 65 | 22.8 | ||||
Unknown | 33 | 4.7 | ||||||
Number of positive SLNs | ||||||||
1 | 488 | 69.5 | 208 | 73.0 | 74 | 61.7 | ||
2 | 161 | 22.9 | 61 | 21.4 | 30 | 25.0 | ||
>2 | 53 | 7.6 | 16 | 5.6 | 16 | 13.3 | ||
Number of negative SLNs | ||||||||
0 | 271 | 38.6 | 36 | 30.0 | ||||
1 | 183 | 26.1 | 17 | 14.2 | ||||
2 | 102 | 14.5 | 20 | 16.7 | ||||
>2 | 146 | 20.8 | 47 | 39.2 | ||||
Size of SLN metastasis (mm) | ||||||||
≤2 | 264 | 92.7 | 44 | 36.7 | ||||
>2 | 21 | 7.4 | 76 | 63.3 | ||||
NSLN positive | ||||||||
+ | 264 | 37.6 | 101 | 35.4 | 45 | 37.5 | ||
− | 438 | 62.4 | 184 | 64.6 | 75 | 62.5 |