Table 4.
Comparison of patient-reported outcomes* among men who underwent radical prostatectomy by robot-assisted laparoscopic radical prostatectomy versus radical retropubic prostatectomy
HRQOL domain** |
All RALP | All RRP |
p value† |
Low-risk RALP |
Low-risk RRP |
p value† |
Intermediate or high-risk RALP |
Intermediate or high-risk RRP |
p value† |
---|---|---|---|---|---|---|---|---|---|
n = 132 | n = 468 | – | n = 64 | n = 263 | – | n = 57 | n = 185 | – | |
Response rate, % |
95.2 | 94.2 | – | 94.4 | 94.3 | – | 96.9 | 94.9 | – |
Urinary incontinence |
74.4 ± 23.0 | 74.4 ± 25.3 | 0.93 | 69.5 ± 24.5 | 75.1 ± 26.0 | 0.42 | 81.7 ± 18.0 | 73.2 ± 24.8 | 0.12 |
Urinary obstruction |
94.5 ± 7.5 | 93.9 ± 9.6 | 0.94 | 95.4 ± 7.6 | 93.8 ± 9.7 | 0.72 | 94.4 ± 7.4 | 93.5 ± 9.9 | 0.86 |
Sexual | 36.8 ± 29.5 | 36.3 ± 29.7 | 0.66 | 39.4 ± 28.7 | 39.7 ± 30.0 | 0.58 | 34.2 ± 30.3 | 30.7 ± 28.1 | 0.84 |
Bowel | 96.3 ± 9.2 | 96.3 ± 7.8 | 0.52 | 96.2 ± 10.4 | 96.3 ± 8.6 | 0.52 | 96.4 ± 8.0 | 96.1 ± 6.9 | 0.84 |
Hormonal/vit ality |
93.5 ± 10.6 | 92.6 ± 11.4 | 0.37 | 94.2 ± 10.1 | 92.9 ± 10.8 | 0.93 | 93.2 ± 10.3 | 92.3 ± 12.1 | 0.57 |
Outcome satisfaction |
89.3 ± 13.3 | 89.5 ± 13.6 | 0.41 | 90.5 ± 11.6 | 89.4 ± 14.3 | 0.86 | 89.9 ± 14.0 | 89.7 ± 12.7 | 0.62 |
HRQOL = health-related quality of life; RALP = robot-assisted laparoscopic radical prostatectomy; RRP = radical retropubic prostatectomy.
Up to 5 men who had RALP and up to 24 men who had RRP were missing one of the HRQOL domains from the questionnaire.
Resulting domain scores for the Expanded Prostate Cancer Index Composite 26 (urinary incontinence, urinary obstruction, sexual, bowel hormonal/vitality) is on a 0–100 scale, with higher values representing a more favorable HRQOL. Resulting scores for the Satisfaction Scale for Cancer Care (outcome satisfaction) is on a 0–100 scale, with higher values representing more satisfaction.
P values represent significance of the surgical technique variable (RALP vs RRP) in multivariable linear models, with HRQOL score as the dependent variable, adjusted for patient age at diagnosis, D’Amico risk group, and time since prostatectomy. The models by risk group were not adjusted for risk group.