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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Innate Immun. 2013 Oct 9;20(7):697–711. doi: 10.1177/1753425913505122

Figure 4.

Figure 4

LBP SNP rs2232613 is associated with altered endotoxin extraction and delivery to MD-2. Cohort II: plasma samples corresponding to LBP SNPs (a) rs2232571, (b) rs2232582, (c) rs2232613 and (d) rs2232618 are shown. Plasma-dependent extraction and transfer of endotoxin monomer to MD-2 was measured and represented as relative LOS capture as described in the ‘Materials and methods’. Values are presented as median relative LOS capture (5–95 percentile with outliers shown). Assay detection limit is signified by dotted line (≤ 1%). Only groups of n≥ 8 were considered for statistical comparisons. Statistical significance was assessed by two-tailed t-test or Mann–Whitney test (parametric or non-parametric distributions, respectively) and indicated as *P < 0.05. LLD: lower limit of detection.