. Author manuscript; available in PMC: 2014 Aug 11.

Published in final edited form as: Mol Psychiatry. 2012 Aug 7;18(8):909–915. doi: 10.1038/mp.2012.109

Table 2.

[¹¹C]Raclopride BP_ND and ΔBP_ND by Diagnostic Group

	Controls (n=15)			DD Patients (n=11)			Group Comparisons^a
ROI	Baseline	Post-amph	ΔBP_ND	Baseline	Post-amph	ΔBP_ND	p BP_ND	p ΔBP_ND
VST	2.52 ± 0.30	2.22 ± 0.31	−12 ± 7%	2.48 ± 0.36	2.28 ± 0.27	−7 ± 8%	0.76	0.18

AST	2.90 ± 0.28	2.59 ± 0.30	−11 ± 6%	2.77 ± 0.35	2.65 ± 0.33	−4 ± 7%	0.29	0.01

preDCA	2.77 ± 0.31	2.51 ± 0.32	−9 ± 6%	2.69 ± 0.35	2.59 ± 0.33	−3 ± 8%	0.57	0.04

preDPU	3.24 ± 0.31	2.84 ± 0.35	−12 ± 6%	3.06 ± 0.37	2.91 ± 0.35	−5 ± 7%	0.19	0.01

postCA	2.19 ± 0.27	1.95 ± 0.19	−11 ± 7%	2.07 ± 0.37	1.97 ± 0.37	−5 ± 7%	0.35	0.04

postPU	3.45 ± 0.35	2.75 ± 0.32	−20 ± 5%	3.20 ± 0.43	2.80 ± 0.42	−12 ± 6%	0.12	<0.01

STR	3.02 ± 0.30	2.60 ± 0.29	−14 ± 5%	2.87 ± 0.37	2.66 ± 0.34	−7 ± 6%	0.25	<0.01

Note. Mean ± Standard Deviation (observed).

AST=associative striatum; DD=dual-diagnosis; post-amph=post-amphetamine; postCA=postcommissural caudate; postPU= postcommissural putamen; preDCA=precommissural dorsal caudate; preDPU=precommissural dorsal putamen; STR=whole striatum; VST=ventral striatum.

Group comparisons of estimated marginal means derived from linear mixed modeling (see text) with the exception of AST and STR; these composite regions were compared with independent-samples t-tests.