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The distortion of helix III by the disulfide bond. (a) Comparison of P2Y12R-AZD1283 (orange) and P2Y12R-2MeSADP (greencyan). (b) Corresponding positions of residues around C973.25 in P2Y12R-AZD1283 (orange) and P2Y12R-2MeSADP (greencyan).
