Table 1.
Patient characteristics
| WHO grade II | WHO grade III | WHO grade IV | |
|---|---|---|---|
|
|
|
|
|
| Variable | n (%) | n (%) | n (%) |
| All | 25 (100) | 26 (100) | 185 (100) |
| Status | |||
| Alive | 11 (44) | 6 (23) | 15 (8) |
| Dead | 14 (56) | 20 (77) | 170 (92) |
| Histology | |||
| Astro | 16 (64) | 16 (62) | 185 (100) |
| Oligo/mix | 9 (36) | 10 (38) | - |
| None | - | - | - |
| Age | |||
| < 60 years | 20 (80) | 14 (54) | 56 (30) |
| > 60 years | 5 (20) | 12 (46) | 129 (70) |
| Gender | |||
| Male | 9 (36) | 19 (73) | 106 (67) |
| Female | 16 (64) | 7 (27) | 79 (43) |
| Performance status | |||
| 0-1 | 18 (72) | 20 (77) | 116 (63) |
| 2/2+ | 7 (28) | 6 (23) | 69 (37) |
| Enhancement | |||
| No | 15 (60) | 2 (8) | 0 (0) |
| Yes | 10 (40) | 24 (92) | 177 (96) |
| Missing | - | - | 8 (4) |
| Midline shift | |||
| No | 10 (40) | 10 (38) | 89 (48) |
| Yes | 15 (60) | 16 (62) | 96 (52) |
| Missing | - | - | - |
| Crossing midline | |||
| No | 23 (92) | 22 (85) | 162 (88) |
| Yes | 2 (8) | 4 (15) | 23 (12) |
| Missing | - | - | - |
| Localization | |||
| Frontal | 17 (68) | 16 (62) | 55 (30) |
| Non-frontal | 8 (32) | 10 (38) | 130 (70) |
| Neurologic deficit | |||
| No | 18 (72) | 16 (62) | 99 (54) |
| Yes | 7 (28) | 10 (38) | 86 (46) |
| Headache | |||
| No | 24 (96) | 20 (77) | 136 (74) |
| Yes | 1 (4) | 6 (23) | 49 (26) |
| Epilepsy | |||
| No | 7 (28) | 18 (69) | 144 (78) |
| Yes | 18 (72) | 8 (31) | 41 (22) |
| Mental disturbance | |||
| No | 22 (88) | 17 (65) | 133 (72) |
| Yes | 3 (12) | 9 (35) | 52 (28) |
| Surgery | |||
| Biopsy | 10 (40) | 7 (27) | 13 (7) |
| Partial | 7 (28) | 14 (54) | 113 (61) |
| Total | 8 (32) | 5 (19) | 59 (32) |
| Post-surgical treatment | |||
| No | 24 (96) | 5 (19) | 31 (17) |
| Yes | 1 (4) | 21 (81) | 154 (83) |
| IDH1 status | |||
| Wildtype | 8 (32) | 17 (65) | 181 (98) |
| Mutated | 17 (68) | 9 (35) | 4 (2) |