Figure 1.

Immunohistochemistry staining for p53, cyclin D1 and Ki-67 in tissue sections of second primary malignancies. Representative photographs of immunohistochemistry staining for p53, Ki-67 and cyclin D1 in second primary breast adenocarcinoma and rectal adenocarcinoma. A. p53 expression in breast adenocarcinoma. B. Ki-67 expression in breast adenocarcinoma. C. p53 expression in rectal adenocarcinoma. D. Ki-67 expression in rectal adenocarcinoma. E. Cyclin D1 expression in rectal adenocarcinoma. 200 x magnification (upper panels) and 400 x magnification of boxed area (lower panels).