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. 2014 Jun 15;7(7):4045–4056.

Table 1.

Baseline characteristics of patients according to average NLR tertiles

Tertile1 (n=230) Tertile2 (n=232) Tettile3 (n=230) P values
(NLR<3.16) (3.16-4.75) (NLR>4.75) 1 vs. 2 1 vs. 3 2 vs. 3 Overall
NLRaverage 2.49±0.52 3.89±0.47 6.87±2.42 <0.001* <0.001* <0.001* <0.001*
Age 57.09±11.57 60.03±11.04 63.69±11.31 0.004* <0.001* 0.001* <0.001*
Body mass index (kg/m2) 25.45±6.13 25.15±5.20 25.14±3.15 0.648 0.660 0.980 0.874
Men/Women 184/46 170/62 192/38 0.076 0.359 0.007* 0.024*
History
    Hypertension 53.91% (124) 64.66% (150) 57.39% (132) 0.019* 0.448 0.113 0.057
    Dyslipidemia 27.83% (64) 30.60% (71) 14.78% (34) 0.483 0.001* <0.001* <0.001*
    Diabetes mellitus 25.65% (59) 27.59% (64) 23.91% (55) 0.635 0.670 0.368 0.666
    Cerebral Stroke 15.22% (35) 15.52% (36) 14.78% (34) 0.929 0.897 0.826 0.976
    Smoking 68.70% (158) 65.95% (153) 69.57% (160) 0.527 0.842 0.405 0.685
    Previous myocardial infarction 6.09% (14) 6.03% (14) 6.96% (16) 0.982 0.703 0.685 0.902
    Previous PTCA 1.74% (4) 0.86% (2) 1.74% (4) 0.431 1.000 0.431 0.660
    History of heart pass 0.43% (1) 0.86% (2) 0.00% (0) 0.485 0.478 0.159 0.371
Admission condition
    Systolic blood pressure (mmHg) 126.20±21.46 128.69±21.25 126.59±23.63 0.692 0.991 0.764 0.678
    Diastolic blood pressure (mmHg) 77.88±13.22 78.92±13.51 76.77±13.37 0.569 0.544 0.237 0.497
    Heart rates (beats/min) 72.33±11.14 76.25±15.81 81.62±17.36 0.013* <0.001* <0.001* <0.001*
    Killip class (≥2) 30.00% (69) 31.90% (74) 50.43% (116) 0.669 <0.001* <0.001* <0.001*
Biochemical measurements
    Peak of CKMB (ng/ml) 384.97±468.69 327.98±577.39 352.82±317.04 0.221 0.238 0.944 0.389
    Peak of creatine kinase (ng/ml) 2278.15±1862.42 2076.35±1710.98 2863.90±2186.00 0.505 0.049* 0.007* 0.019*
    Creatinine (mg/dl) 1.09±0.96 1.11±0.97 1.12±0.31 0.709 0.669 0.956 0.898
    Cholesterol (mg/dl) 193.76±58.28 188.45±43.26 180.73±36.40 0.235 0.011* 0.136 0.038*
    Triglyceride (mg/dl) 205.85±137.12 150.62±101.77 136.44±80.81 0.001* <0.001* 0.388 <0.001*
    HDL (mg/dl) 43.35±14.72 42.36±11.20 40.79±9.67 0.547 0.130 0.335 0.308
    LDL (mg/dl) 119.07±40.61 116.82±35.18 112.33±33.30 0.654 0.189 0.363 0.404
    Glucose (mg/dl) 156.79±64.59 163.11±79.34 177.79±79.97 0.376 0.004* 0.039* 0.012*
Hematological measurements on admission
    Leukocyte counts (109/L) 9.04±2.55 10.41±3.34 11.17±2.87 0.001* <0.001* 0.045* <0.001*
    Neutrophils (109/L) 6.11±2.28 8.25±2.66 9.77±2.75 <0.001* <0.001* <0.001* <0.001*
    lymphocytes (109/L)) 2.56±1.03 1.80±0.66 1.14±0.37 <0.001* <0.001* <0.001* <0.001*
    Monocytes (109/L) 0.33±0.18 0.30±0.21 0.22±0.16 0. 389 <0.001* <0.001* <0.001*
    Platelets (109/L) 212.19±56.14 210.20±61.33 199.61±56.38 0.827 0.173 0.245 0.341
    Red blood cell counts (1012/L) 4.57±0.52 4.54±0.59 4.53±0.57 0.660 0.553 0.866 0.829
    Hemoglobin (g/L) 140.08±21.05 138.09±16.46 140.29±17.9 0.453 0.940 0.396 0.644

T1 NLRaverage<3.16, T2 3.16≤NLRaverage≤4.75, T3 NLRaverage>4.75. Data shown are % (n), median (IQR) or mean ± SD.

*

P<0.05.

CK-MB: MB isoenzyme of creatine kinase; HDL: High-density lipoprotein cholesterol; LDL: Low-density lipoprotein cholesterol; NLR: neutrophil-to-lymphocyte ratio; PCTA: percutaneous transluminal coronary angioplasty.